Fatal haemoptysis in a case of lymphomatoid granulomatosis treated with rituximab.

نویسندگان

  • S Jaffre
  • F Jardin
  • S Dominique
  • E Duet
  • Ph Hubscher
  • A Genevois
  • F Corne
  • S Bota
  • G Nouvet
  • L Thiberville
چکیده

Lymphomatoid granulomatosis is a rare angiocentric and angiodestructive disease, which commonly involves the lungs but also the brain, kidneys, liver and skin. This report describes the case of a 33-yr-old female with an aggressive form of lymphoid granulomatosis treated with an anti-CD20 antibody. Dramatic radiological improvement was seen at the fourth week. However, the patient died at home 1 month after the last rituximab administration from a massive haemoptysis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rituximab for pulmonary lymphomatoid granulomatosis which developed as a complication of methotrexate and azathioprine therapy for rheumatoid arthritis

We report the case of a patient with Rheumatoid Arthritis [RA] presenting with clinical-pathological and radiological features of Pulmonary Lymphomatoid Granulomatosis (PLG). This is a rare lung disorder characterized by multiple nodular lesions with lymphocytic invasion of vascular walls. We present one such case of PLG secondary to Methotrexate and Azathioprine therapy, who was successfully t...

متن کامل

Pulmonary lymphomatoid granulomatosis. A rare entity in the differential diagnosis of pulmonary nodules.

2. Guiñazú Álvarez A, Matteoda M, Tempra A. Granulomatosis linfomatoidea: manifestaciones pulmonares de una entidad infrecuente. RAR. 2006;70:289–92. 3. Frazier AA, Rosado-de-Christenson ML, Galvin JR, Fleming MV. Pulmonary angiitis and granulomatosis: radiologic–pathologic correlation. Radiographics. 1998;18:687–710. 4. Ammannagari N, Gao Z, Deng C, O’Connor O. Lymphomatoid granulomatosis: a d...

متن کامل

Pulmonary Lymphomatoid Granulomatosis. A Rare Entity in the Differential Diagnosis of Pulmonary Nodules

2. Guiñazú Álvarez A, Matteoda M, Tempra A. Granulomatosis linfomatoidea: manifestaciones pulmonares de una entidad infrecuente. RAR. 2006;70:289–92. 3. Frazier AA, Rosado-de-Christenson ML, Galvin JR, Fleming MV. Pulmonary angiitis and granulomatosis: radiologic–pathologic correlation. Radiographics. 1998;18:687–710. 4. Ammannagari N, Gao Z, Deng C, O’Connor O. Lymphomatoid granulomatosis: a d...

متن کامل

Oral lymphomatoid granulomatosis, the first sign of a ‘rare disease’: a case report

INTRODUCTION Lymphomatoid granulomatosis is an uncommon Epstein-Barr virus-positive B-cell lymphoma, an angiocentric-destructive process with a predominant T-cell background. Lymphomatoid granulomatosis is listed among rare diseases. Common localization is in the lungs. Lymphomatoid granulomatosis with oral involvement is described in only two reports. In this report, we describe a third case o...

متن کامل

Lymphomatoid Granulomatosis with Spinal Involvement after Childhood Acute Lymphoblastic Leukemia

Lymphomatoid granulomatosis (LYG) is a lymphoproliferative disease involving the lungs most frequently; however, it may also involve the kidneys, skin and especially the central nervous system. Unique initial presentation of spinal involvement is extremely rare and epidural lesion of thoracic spine has not been reported. The prognosis for LYG has been reported to be poor, and there currently ex...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The European respiratory journal

دوره 27 3  شماره 

صفحات  -

تاریخ انتشار 2006